Centre for Population Genomics

Defining early-onset glaucomagenetic etiologies

(PI: Professor Janey Wiggs, Massachusetts Eye and Ear, Harvard Medical School)

Individuals who develop glaucoma before age 40 (early-onset glaucoma) have few treatment options and are most likely to become blind during their lifetimes. This NIH-funded project will use whole genome sequencing on 1500 individuals or family members affected by early-onset glaucoma, with the aim of revealing new genetic causes, improving risk prediction and genetic counselling, and identifying new and potentially curative therapeutic targets.